Publications

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Stüfchen, I., Beckervordersandforth, R., Fischer, S., Kappelmann‐Fenzl, M., Bosserhoff, A. K., & Beyer, F. (2022). Two novel CreERT2 transgenic mouse lines to study melanocytic cells in vivo. Pigment Cell & Melanoma Research, 35(6), 613-621. doi: 10.1111/pcmr.13061

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Karpf, J., Unichenko, P., Chalmers, N., Beyer, F., Wittmann, M. T., Schneider, J., ... & Beckervordersandforth, R. (2022). Dentate gyrus astrocytes exhibit layer-specific molecular, morphological and physiological features. Nature Neuroscience, 1-13. doi: 10.1038/s41593-022-01192-5

 

Schneider, J., Weigel, J., Wittmann, M. T., Svehla, P., Ehrt, S., Zheng, F., ... & Beckervordersandforth, R. (2022). Astrogenesis in the murine dentate gyrus is a life‐long and dynamic process. The EMBO Journal, e110409. doi: 10.15252/embj.2021110409

 

Beyer F, Lüdje W, Karpf J, Saher G, Beckervordersandforth R (2021) Distribution of Aldh1L1-CreERT2 recombination in astrocytes versus neural stem cells in the neurogenic niches of the adult mouse brain. Front. Neurosci. 15:713077.

doi: 10.3389/fnins.2021.713077

 

Fiebig C, Keiner S, Ebert B, Schäffner I, Jagasia R, Lie DC, Beckervordersandforth R (2019) Mitochondrial dysfunction in astrocytes impairs the generation of reactive astrocytes and enhances neuronal cell death in the cortex upon photothrombotic lesion. Front. Molecular Neurosci 12:40. doi: 10.3389/fnmol.2019.00040

 

Schäffner I, Minakaki G, Khan MA, Balta EA, Schlötzer-Schrehardt U, Schwarz T, Beckervordersandforth R, Winner B, Webb AE, DePinho R, Paik J, Wurst W, Klucken J, and Lie DC (2018) FoxO function is essential for maintenance of autophagic flux and neuronal morphogenesis in adult neurogenesis. Neuron 2018 Sep 19;99(6):1188-1203. doi: 10.1016/j.neuron.2018.08.017

 

Pons-Espinal M, de Luca E, Marzi MJ, Beckervordersandforth R, Armirotti A, Nicassio F, Fabel K, Kempermann G, De Pietri Tonelli D (2017) Synergistic functions of miRNAs determine neuronal fate of adult neural stem cells. Stem Cell Reports, 2017 April 11; 8(4):1046-1061. doi: 10.1016/j.stemcr.2017.02.012

 

Beckervordersandforth R#*, Ebert B*, Shin J, Fiebig C, Moss J, Moore DL, Ghosh L, Trinchero MF, Stockburger C, Friedland K, Steib K, Schäffner I, von Wittgenstein J, Keiner S, Redecker C, Hölter SM, Wurst W, Jagasia R, Schinder AF, Jessberger S, Ming GL, Song H, Toni N, Lie DC# (2017) Role of mitochondrial metabolism in the control of early lineage progression and aging phenotypes in adult hippocampal neurogenesis. Neuron 2017 Feb 8 93: 1-14. doi: 10.1016/j.neuron.2016.12.017

# Corresponding authors

* Equal contribution

 

Gebara E, Bonaguidi MA*, Beckervordersandforth R*, Sultan S, Udry F, Gijs PJ, Lie DC, Ming G, Song S, and Toni N. (2015) Heterogeneity of radial glia-like cells in the adult hippocampus. Stem Cells 2016 Jan 1. doi: 10.1002/stem.2266

* Equal contribution

 

Fukusumi Y, Meier M, Götz S, Matheus F, Irmler M, Beckervordersandforth R, Faus-Kessler T, Minina E, Rauser B, Zhang J, Arenas E, Andersson E, Niehrs C, Beckers J, Simeone A, Wurst W, and Prakash N. (2015) Dickkopf 3 promotes the differentiation of a rostrolateral midbrain dopaminergic neural subset in vivo and from pluripotent stem cells in vitro in mouse. J Neurosci. 2015 September 30;35(39):13385-13401.

doi: 10.1523/JNEUROSCI

Lead experimentalist for FACS analysis

 

Karow M, Schichor C, Beckervordersandforth R, and Berninger B. (2014) Lineage-reprogramming of pericyte-derived cells of the adult human brain into induced neurons. Journal of visualized experiments JoVE 01/2014. 

doi: 10.3791/51433

Lead experimentalist for FACS analysis

 

Beckervordersandforth, R#, Deshpande A, Schäffner I, Huttner HB, Lepier A, Lie CD, and Götz, M. (2014) In vivo targeting of adult neural stem cells in the dentate gyrus by a split-Cre approach. Stem Cell Reports, 2014 Feb 6; 2(2);153-162. 

doi: 10.1016/j.stemcr.2014.01.004

# Corresponding author

 

Fischer J*, Beckervordersandforth R*, Tripathi P, Steiner-Mezzadri A, Ninkovic J, and Götz, M. (2011) Prospective isolation of the adult neural stem cells and their progeny from the mouse subependymal zone. Nat Protoc. 2011 Nov 17 ;6(12) :1981-9.

doi: 10.1038/nprot.2011.412

* Equal contribution

 

Costa MR, Ortega F, Brill MS, Beckervordersandforth R, Petrone C, Schroeder T, Götz M, and Berninger B. (2012) Continuous live imaging of adult neural stem cell division and lineage progression in vitro. Development, 138 (2011), 1057-1068 (2011). doi.org/10.1242/jcs.088575

 

Eilken H, Rieger MA, Hoppe PS, Hermann AC, Smejkal BM, Drew EC, Thum M, Ninkovic J, Beckervordersandforth R, and Schroeder T. (2011) Continuous long-term detection of live cell surface markers by 'in culture' antibody staining. Nature Protocol Exchange 2011 Jan (28); doi:10.1038/protex.2011.205

 

Beckervordersandforth R*, Tripathi P*, Ninkovic J*, Bayam E, Lepier A, Stempfhuber B, Kirchhoff F, Hirrlinger J, Haslinger A, Lie DC, Beckers J, Yoder B, Irmler M, and Götz M. (2010) In vivo fate mapping and expression analysis reveals molecular hallmarks of prospectively isolated adult neural stem cells. Cell Stem Cell. 2010 Dec 3;7(6):744-58. doi: 10.1016/j.stem.2010.11.017

* Equal contribution

 

Gajera CR, Emich H, Lioubinski O, Christ A, Beckervordersandforth-Bonk R, Yoshikawa K, Bachmann S, Christensen EI, Götz M, Kempermann G, Perterson AS, Willnow TE, and Hammes A. (2010) LRP2 in ependymal cells regulates BMP signalling in the adult neurogenic niche. J Cell Sci. 2010 Jun 1;123(Pt11):1922-30. Epub 2010 May11.

doi: 10.1242/jcs.065912

 

Beckervordersandforth RM, Rickert C, Altenhein B, and Technau GM. (2008) Subtypes of glial cells in the Drosophila embryonic ventral nerve cord as related to lineage and gene expression. Mech Dev. 2008 May-Jun;125(5-6):542-57. Epub 2008 Jan 8. doi: 10.1016/j.mod.2007.12.004

 

von Hilchen CM, Beckervordersandforth RM, Rickert C, Technau GM, and Altenhein B. (2008) Identity, origin, and migration of peripheral glial cells in the Drosophila embryo. Mech Dev. 2008 Mar-Apr;125(3-4):337-52. Epub 2007 Nov 1. doi: 10.1016/j.mod.2007.10.010

 

 

 

BOOK CHAPTERS

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Schneider J, Karpf J, Beckervordersandforth R# (2019) Role of Astrocytes in the neurogenic niches. Methods in Molecular Biology, vol. 1938 (2019).

doi: 10.1007/978-1-4939-9068-9_2

 

Beckervordersandforth R, Zhang CL, and Lie DC. 2015

Transcription factor-dependent control of adult hippocampal neurogenesis

Cold Spring Harb Perspecti. Biol doi: 10.1101/cshperspect.a018879.

doi: 10.1101/cshperspect.a018879

 

 

REVIEW/PREVIEW

Beckervordersandforth R and Rolando C (2020) Untangling human neurogenesis to understand and counteract brain disorders. Current Opinion in Pharmacology 2020. 50:67-73. doi: 10.1016/j.coph.2019.12.002

 

Beckervordersandforth R (2017) Newborn neurons in the aged brain - scarce and slow but highly plastic. Cell Reports 21, October 31, 2017. doi: 10.1016/j.celrep.2017.10.049

 

Beckervordersandforth R (2017) Mitochondrial metabolism-mediated regulation of adult neurogenesis. Brain Plasticity 3 (2017) 73-87. doi: 10.3233/BPL-170044

 

Beckervordersandforth R, Häberle BM, and Lie DC. (2015) Metabolic regulation of adult stem cell-derived neurons. Front.Biol., 2015, 10(2):107-116. doi: 10.1007/s11515-015-1351-5